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When infections occur in the body, stem cells in the blood often jump into action by multiplying and differentiating into mature immune cells that can fight off illness. But repeated infections and inflammation can deplete these cell populations, potentially leading to the development of serious blood conditions such as cancer...

Cancers of all types become most deadly when they metastasize and spread tumors throughout the body. Once cancer has reached this stage, it becomes very difficult for doctors to locate and treat the numerous tumors that can develop. Now, researchers at the University of Missouri have found a way to create radioactive nanoparticles that target lymphoma tumor cells wherever they may be in the body...

A novel transcriptome-based classification of colon cancer that improves the current disease stratification based on clinicopathological variables and common DNA markers is presented in a study published in PLOS Medicine this week. (A transcriptome is all RNA produced by a population of cells.) Pr...

University of Louisville researchers have uncovered how to create nanoparticles using natural lipids derived from grapefruit, and have discovered how to use them as drug delivery vehicles. UofL scientists Huang-Ge Zhang, D.V.M., Ph.D., Qilong Wang, Ph.D., and their team have published their findings in Nature Communications. Lipids derived from grapefruit...

The surgical management of non-small cell lung cancer (NSCLC) in U.S. hospitals varies widely depending on the race of the patient, according to a new study. "In most patients, the initial treatment for Stage I and Stage II NSCLC is surgery," said researcher Jayanth Adusumalli, MBBS, of the Creighton University Medical Center in Omaha, Nebraska...

New research suggests that a compound abundant in the Mediterranean diet takes away cancer cells' "superpower" to escape death. By altering a very specific step in gene regulation, this compound essentially re-educates cancer cells into normal cells that die as scheduled...

Recently Angelina Jolie announced that she underwent a double mastectomy and reconstructive surgery in order to reduce her risk of developing breast cancer, she said she "hopes other women can benefit from my experience". When she found out what her odds of developing cancer were, Jolie became proactive and decided to reduce her risk to a minimum...

Discovering that mouse hair has a circadian clock - a 24-hour cycle of growth followed by restorative repair - researchers suspect that hair loss in humans from toxic cancer radiotherapy and chemotherapy might be minimized if these treatments are given late in the day...

Researchers from the Masonic Cancer Center, University of Minnesota, and the University's Brain Tumor Program, have developed a new mouse model of malignant peripheral nerve sheath tumors (MPNST) that allow them to discover new genes and gene pathways driving this type of cancer. The research was published this week in the journal Nature Genetics...

New research suggests that a compound abundant in the Mediterranean diet takes away cancer cells' "superpower" to escape death. By altering a very specific step in gene regulation, this compound essentially re-educates cancer cells into normal cells that die as scheduled...

Recently Angelina Jolie announced that she underwent a double mastectomy and reconstructive surgery in order to reduce her risk of developing breast cancer, she said she "hopes other women can benefit from my experience". When she found out what her odds of developing cancer were, Jolie became proactive and decided to reduce her risk to a minimum...

But the absolute excess for all cancers combined is low Young people who undergo CT scans are 24% more likely to develop cancer compared with those who do not, a study published today on bmj.com suggests. However the absolute excess for all cancers combined was low, at 9.38 for every 100,000 person years of follow-up...

In a new study described in the journal Oncogene, researchers reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumor growth. Scientists call this Jekyll-and-Hyde molecule NF-kappa B. In healthy cells, it is a powerful "first responder," a vital part of the body's immune and inflammatory responses...

Confirmed: Primary endpoint of significantly improving overall survival not met Merck Serono, a division of Merck, Darmstadt, Germany, today announced detailed results from the randomized Phase III START* trial of its investigational MUC1 antigen-specific cancer immunotherapy L-BLP25 (formerly referred to as Stimuvax) in patients with unresectable, locally advanced Stage III...

In their quest to learn more about the variability of cells between and within tissues, biomedical scientists have devised tools capable of simultaneously measuring dozens of characteristics of individual cells. These technologies have led to new challenges, however, as scientists now struggle with how to make sense of the resulting trove of data. Now a solution may be at hand...

A new measure of the heterogeneity - the variety of genetic mutations - of cells within a tumor appears to predict treatment outcomes of patients with the most common type of head and neck cancer...

In their quest to learn more about the variability of cells between and within tissues, biomedical scientists have devised tools capable of simultaneously measuring dozens of characteristics of individual cells. These technologies have led to new challenges, however, as scientists now struggle with how to make sense of the resulting trove of data. Now a solution may be at hand...

Research presented at Digestive Disease Week® (DDW) explores new methods for managing digestive health through diet and lifestyle. Individuals suffering from Crohn's disease are often plagued by reduced muscle strength, fatigue and poor quality of life. These symptoms can remain even when patients are in remission...

A ground-breaking advance in colonoscopy technology signals the future of colorectal care, according to research presented at Digestive Disease Week® (DDW). Additional research focuses on optimizing the minimal withdrawal time for colonoscopies and exploring safer methods for removing polyps. During colonoscopy, doctors use a device called a colonoscope to examine the colon...

Many women in Texas who are found to have an abnormality on routine mammogram or discover a lump in one of their breasts end up having an old-fashioned surgical biopsy to find out whether the breast abnormality is malignant. Since 2001, national expert panels have recommended that the first course of action for women with breast lumps or masses should be minimally invasive biopsy...