Medical News Today: Oncology News
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Updated: 9 hours 32 min ago
Gene Expression Signature In Urine For Diagnosing And Assessing Aggressiveness Of Bladder Urothelial Carcinoma
The current diagnostic systems of bladder cancer are based upon a combination of urine cytology and direct observation of the bladder by cystoscopy. The latter is, in actual fact, the main diagnostic and tumour follow-up technique. It is performed transurethrally, and consequently it is an invasive approach, quite uncomfortable for most patients...
Quantification Of Tumor Cell Burden By Analysis Of Single Cell Lymph Node Disaggregates In Metastatic Prostate Cancer
UroToday.com - In the July, 2010 edition of The Prostate, David Schilling and colleagues from the Department of Urology, under the direction of Arnulf Stenzel, in Tuebingen, Germany report on a novel methodology to assess degree of lymph node (LN) metastasis in patients with prostate cancer (CaP)...
Consequential Late Effects After Radiotherapy For Prostate Cancer - A Prospective Longitudinal Quality Of Life Study
UroToday.com - External beam radiotherapy (EBRT) is a well-established curative treatment for localized prostate cancer. Acute and late toxicity rates after EBRT can be considerable and have been the subject of many studies. Dose-volume effect relationships have been described extensively. In the early years of radiotherapy, the "skin erythema dose" was used for the definition of tolerable doses...
Risk Of Thromboembolic Diseases In Men With Prostate Cancer: Results From The Population-based PCBaSe Sweden
UroToday.com - Endocrine treatment (ET), which interrupts testosterone regulation of the prostate tumor, is the cornerstone treatment for men with locally advanced or metastatic prostate cancer. A number of metabolic side-effects have been reported including increased body weight, insulin resistance, dyslipidemia, and hyperglycemia...
Associations Of Aspirin, NSAID And Paracetamol Use With PSA-detected Prostate Cancer: Findings From A Large, Population-based, Case-control Study
UroToday.com - In the online edition of the International Journal of Cancer, Dr. Ali Murad and colleagues report that non-steroidal anti-inflammatory drugs (NSAIDs) do not decrease the risk of PSA-detected prostate cancer (CaP). The premises for the study are reports that cyclooxygenase-2 is an enzyme that facilitates inflammation and is overexpressed in CaP...
Is Pure Laparoscopic Radical Cystectomy Still An Attractive Solution For The Treatment Of Muscle-invasive Bladder Cancer?
UroToday.com - Radical cystectomy is the most effective treatment for patients with organ confined muscle invasive or recurrent high grade non muscle invasive bladder cancer...
Melanoma Rates Among Minorities In Florida Differ From National Trends
Racial and ethnic trends in the skin cancer melanoma appear different in Florida than from national estimates, with higher incidence rates among Hispanic men and non-Hispanic black women but lower rates among Hispanic women, according to a report in the July issue of Archives of Dermatology, one of the JAMA/Archives journals...
Study Finds Childhood Cancer Survivors Still Have Higher Risk Of Death 25 Years Later, From Cancer, Circulatory Diseases
Follow-up of a group of British childhood cancer survivors indicates they have an increased risk of death from second primary cancers and cardiac and cerebrovascular causes more than 25 years after their initial cancer diagnosis, according to a study in the July 14 issue of JAMA...
Telephone-Based Care Management Program Helps Cancer Patients With Pain, Depression
Cancer patients receiving care in geographically dispersed urban and rural oncology practices who participated in a program that included telephone-based care management and home-based automated symptom monitoring had greater improvement in pain and depression compared to patients who received usual care, according to a study in the July 14 issue of JAMA...
New GP Guide For Cancer Screening, Australia
Cancer Council Australia has published a quick reference guide to assist GPs and other health professionals in the screening and surveillance of specific cancers. The guide provides evidence-based recommendations on which cancers are suitable for population screening, methods and frequency of screening and whether a government screening program exists...
Cancer Conundrum Revealed By Missing Gene Called 'Puma'
Walter and Eliza Hall Institute researchers in Melbourne, Australia, have made a discovery that has upended scientists' understanding of programmed cell death and its role in tumour formation. Programmed cell death, also called apoptosis, is an important process in human biology as it removes unwanted and damaged cells from our bodies...
Scientists Find Gas Pedal - And Brake - For Uncontrolled Cell Growth
Researchers at the University of California, San Diego School of Medicine have identified a new way to regulate the uncontrolled growth of blood vessels, a major problem in a broad range of diseases and conditions. The findings are published in the online edition of Nature Medicine by David A...
Path That Stops Cells Consuming Themselves For Energy May Help Understanding Of Cancer And Aging
US researchers have discovered a biological path that is essential for maintaining normal means of energy production in cells and may help us better understand metabolic processes in cancer and aging; cells use the path to shuttle calcium in and out of mitochondria, the tiny energy generators inside cells, and when it breaks down, cells consume themselves to get the energy they need...
Contract Supports The Development Of A New Class Of Drugs That Will Help Enhance Soldiers' Performance At High Altitude
Jonathan Stamler, MD, Director of the Institute for Transformative Molecular Medicine and the Robert S. and Sylvia K. Reitman Family Foundation Distinguished Chair in Cardiovascular Innovation at the Case Western Reserve University and University Hospitals Harrington-McLaughlin Heart & Vascular Institute, has recently received a $4...
A Potential Chemotherapeutic Drug To Treat Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, particularly in China. However, HCC remains one of the more difficult cancers to treat. It is important to screen for new anti-cancer drugs. A number of dietary compounds possess anti-cancer properties. These dietary compounds may modify the activity of specific targets that control cell proliferation and apoptosis...
'Guardian Of The Genome': Protein Helps Prevent Damaged DNA In Yeast
Like a scout that runs ahead to spot signs of damage or danger, a protein in yeast safeguards the yeast cells' genome during replication - a process vulnerable to errors when DNA is copied - according to new Cornell research...
Herpes Virus Treats Head And Neck Cancer Patients
A genetically engineered cold sore virus has been used to treat head and neck cancer patients in a Phase I/II clinical trial run by The Institute of Cancer Research (ICR) and The Royal Marsden NHS Foundation Trust. The herpes simplex virus, known as OncoVEX and owned by BioVex Inc, had been modified so it multiplies inside cancer cells but not healthy cells...
Therapies For Heart Disease And Cancer May Benefit From Snake Venom Studies
Researchers seeking to learn more about stroke by studying how the body responds to toxins in snake venom are releasing new findings that they hope will aid in the development of therapies for heart disease and, surprisingly, cancer...
Swimmers Make A Splash For A Good Cause
More than 200 swimmers took to the shores of Lake Michigan for the annual Swim Across America (SAA) fundraiser earlier this month. The event raised money for cancer research, prevention and treatment at Loyola University Health System's Cardinal Bernardin Cancer Center (CBCC)...
NICE Gives Green Light To MabThera(R) (Rituximab) For Wider Use In Patients With Most Common Chronic Leukaemia
The National Institute for Health and Clinical Excellence (NICE) extended its recommendation for the use of targeted antibody MabThera® (rituximab) to include people with relapsed and difficult-to-treat (refractory) chronic lymphocytic leukaemia (CLL) except where patients have received the full therapeutic dose of MabThera in the first line setting or are refractory to fludarabine...