Medical News Today: Colorectal Cancer News
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Updated: 4 hours 55 min ago
Non-infectious illnesses like cancer and cardiovascular diseases are rising globally, but they are hard to diagnose because of lack of biomarkers, and in countries with poor infrastructure, expensive diagnosis using mammograms and colonoscopy is not available to many.
Chemotherapies are cancer treatments that work by inducing lesions in the DNA of tumour cells in order to inhibit their proliferation. However, the body naturally tries to repair these lesions, and thus reduces the efficacy of chemotherapy. Blocking the mechanisms for DNA repair would help to potentiate chemotherapy by reducing the resistance of cells to treatment.
New research published in Nature Communications details the discovery of a potential new drug that selectively kills dormant cancer cells in tumors by inducing mitochondrial dysfunction.The research team, led by Prof.
While new and better treatments have improved the odds of survival for patients diagnosed with late stage colorectal cancer, that progress has been largely confined to non-Hispanic whites and Asians and those under age 65, according to a new study. American Cancer Society researchers led by Helmneh Sineshaw, M.D.
University of Adelaide research has shown for the first time that grape seed can aid the effectiveness of chemotherapy in killing colon cancer cells as well as reducing the chemotherapy's side effects.
Hope for development of drugs to stall the growth of K-Ras cancers, previously deemed impossible to treat
NYU Langone Medical Center researchers have found a biological weakness in the workings of the most commonly mutated gene involved in human cancers, known as mutant K-Ras, which they say can be exploited by drug chemotherapies to thwart tumor growth.
Obesity is a known risk factor for many cancers including colon cancer, yet the reasons behind the colon cancer link have often remained unclear.
Tests that require patients to collect a single stool sample at home and then send it to a lab for analysis will detect about 79 percent of colorectal cancers, according to a new evidence review published in the Annals of Internal Medicine.
Repeat colonoscopy examined in patients with polyps referred for surgery without biopsy-proven cancer
A new study reports that in the absence of biopsy-proven invasive cancer, a second colonoscopy done at an expert center may be appropriate to reevaluate patients referred for surgical resection. In the study, 71 percent of the lesions referred for surgery were noncancerous polyps (growths in the colon) and were treatable endoscopically.
Previous research has suggested that a diet rich in fiber may reduce the risk of colon inflammation and cancer. But new research suggests that niacin, also known as vitamin B3, may also help protect against these conditions.The research team, including co-author Dr.
Johns Hopkins scientists say a previously known but little studied chemical compound targets and shuts down a common cancer process. In studies of laboratory-grown human tumor cell lines, the drug disrupted tumor cell division and prevented growth of advanced cancer cells.In a study described in the journal Cancer-Cell, Marikki Laiho, M.D., Ph.D.
Advantage in overall survival, but disadvantage in severe side effectsRegorafenib (trade name: Stivarga) has been approved in Germany since August 2013 for adults with metastatic colorectal cancer in whom previous treatments are no longer effective or for whom these alternatives are not an option.
Among patients who had undergone curative surgery for primary colorectal cancer, the screening methods of computed tomography and carcinoembryonic antigen each provided an improved rate of surgical treatment of cancer recurrence compared with minimal follow-up, although there was no advantage in combining these tests, according to a study in the January 15 issue of JAMA.
A new method for analysing biological samples based on their chemical makeup is set to transform the way medical scientists examine diseased tissue.When tests are carried out on a patient's tissue today, such as to look for cancer, the test has to be interpreted by a histology specialist, and can take weeks to obtain a full result.
In a large study of women's health, postmenopausal women who followed a healthy lifestyle were at a third lower risk of death, including a 20% smaller chance of dying from cancer, than women who did not follow guidance on diet, weight, physical activity, and alcohol intake.
Researchers at Cleveland Clinic have developed a new tool called CRC-PRO that allows physicians to quickly and accurately predict an individual's risk of colorectal cancer, as published in the current edition of the Journal of the American Board of Family Medicine.